Automatic saving (autosaving) has become the norm not only in games but in computer software. It's a great thing: no one misses losing their entire book report because Microsoft Word didn't autosave it. Autosaving can be especially helpful to players with mobility disabilities who find menus cumbersome to navigate, or players with cognitive disabilities who forget to save their game. Remind players that the game autosaves before they begin playing so they don't get confused when they can't find the save button in the menu.
In some games, especially adventure games, autosaving needs to occur after a mission is completed or a specific checkpoint is reached. Make sure players know the game is autosaving by showing a toast or small tool tip that doesn't detract from the game.